Tardive dystonia due to aripiprazole use in a neuroleptic-naive patient.
نویسنده
چکیده
To the Editor: Lungu et al1 published the first 2 cases of tardive dyskinesia due to aripiprazole in neuroleptic-naive subjects. Both of these subjects had tardive dystonia. One, a 19-year-old woman, had fragile X syndrome and developed her problem after 3 months of aripiprazole treatment. The other, a 56-year-old man, had no preexisting neurologic disorder and developed his movements after 18 months of aripiprazole treatment. Although other tardive syndromes have been ascribed to aripiprazole,2–4 all of the individuals had prior exposure to dopamine receptor–blocking drugs. The following is an additional case of tardive dystonia due to aripiprazole in a neuroleptic-naive woman with no history of neurologic problems.
منابع مشابه
Tardive Dystonia Related with Aripiprazole
Tardive dystonia is characterized by sustained, generally slow involuntary twisting movements. It is estimated to occur at a frequency of 1% to 4% among patients who are taking an antipsychotic agent. Unlike the first generation antipsychotics, the second generation antipsychotics are less likely to cause neuroleptic-induced movement disorder. For aripiprazole, only a few cases have been report...
متن کاملRemission of irreversible aripiprazole-induced tardive dystonia with clozapine: a case report
BACKGROUND Aripiprazole can cause irreversible tardive dystonia in some individuals, and additional intervention is sometimes needed. Here, we report the first case of aripiprazole-induced irreversible tardive dystonia in which complete recovery of motor function was achieved using the antipsychotic drug clozapine. CASE PRESENTATION A 24-year-old man with bipolar disorder was treated with ari...
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Tardive dystonia is a side effect of dopamine receptor-blocking agents, which are mainly used as antipsychotic drugs. The treatment of tardive dystonia is difficult and often unsuccessful. An 82-year-old woman experienced mandibular deviation to the left due to spasm of the masticatory muscles with involuntary chewing movement and Parkinsonism. She had been treated with sulpiride for motility d...
متن کاملEfficacy of aripiprazole in antidepressants-induced tardive dystonia and tardive dyskinesia: a case report.
Tardive syndromes (TDS) are a group of movement disorders. Tardive dyskinesia is the best-known type of TDS. Another type of TDS is tardive dystonia. TDS cause body parts to move uncontrollably. Tardive dyskinesia and tardive dystonia are caused by dopamine receptor blocking agents, mostly antipsychotics but occasionally antidepressants (Jankovic 1995). However, tardive dystonia associated with...
متن کاملA Case of Aripiprazole Induced Tardive Dyskinesia in a Neuroleptic-Naïve Patient with Two Years of Follow Up
Tardive dyskinesia (TD) is arguably the most serious and potential irreversible side effect of antipsychotic medication. Traditionally first generation antipsychotics are the neuroleptics considered to have higher risk of TD as compared to second and third generation antipsychotics. Aripiprazole is a third-generation antipsychotic with a novel mechanism of action. Risk of developing TD with use...
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ورودعنوان ژورنال:
- The Journal of clinical psychiatry
دوره 71 5 شماره
صفحات -
تاریخ انتشار 2010